Nitric Oxide Supplements and Blood Pressure Medications: Clinical Guidelines

Because L-citrulline and L-arginine support natural endothelial vasodilation, they can modestly lower systemic vascular resistance. For individuals taking prescription antihypertensives or nitrates, additive hypotensive effects can occur.

Physician Consultation Mandate

Always review your complete supplement regimen with your prescribing cardiologist or primary care physician prior to initiating nitric oxide precursors.